橄榄-桥脑-小脑萎缩磁共振成像T_2加权像“纵线”征

Vertical line sign on T2WI in olivopontocerebellar atrophy

目的:本文收集47例橄榄-桥脑-小脑萎缩(OPCA)患者MR图像,除T1WI发现特征性形态改变外,在T2WI上发现桥脑有纵行线样高信号,我们称之为“纵线”征。材料与方法:47例OPCA患者,30例进行低场磁共振扫描,17例进行高场磁共振扫描;随机抽样因其他原因而进行头部磁共振检查的病例100例作为对照。结果:47例OPCA患者MR图像T2WI上可见位于桥脑至延髓上部贯穿于脑干前后径的连续性细线样高信号41例,高低场无显著性差异。结论:“纵线”征是OPCA的一种特征性异常信号,其病理基础尚不知,有待于进一步病理学或其他方法加以证实。

Objective: To analyze the MR appearance of OPCA in 47 cases. A verticle hyperintense line in pons on T2WI were found. We called it'verticle line'sign. Methods: Of the 47 cases, 30 were examined by low field and 17 were scanned by high field MR system. These were compared with 100 normal cases without brain disease proved as control who were randomly selected. Results: In 47 cases of OPCA, a vertical continuous hyperintense line run from anterior to posterior of pons and medulla were seen in 41 cases. There was no significant differences between low and high field. Conclusion: The hyperintense verticle line sign is characteristic in OPCA, but the pathologic base is still not clear.