重度妊高征并发腹水48例临床分析

Clinical Analysis of 48 Cases of Severe Pregnancy Induced Hypertesion Complicated by Ascites

目的 :分析重度妊娠高血压综合征 (简称妊高征 )并发腹水的临床特点和防治方法。方法 :将我院 1996年 1月～ 2 0 0 2年 12月间 2 0 4例重度妊高征分为并发腹水组 (A组 ,4 8例 )和未并发腹水组 (B组 ,15 6例 ) ,比较其临床特点。结果 :A、B两组间比较 ,终止妊娠的时间、肝功能检查总蛋白、白蛋白、白 /球比值、乳酸脱氢酶、血肌酐、2 4小时尿蛋白定量、宫内死胎发生率、新生儿早产发生率、孕产妇并发症的发生率差异有显著性 (P <0 .0 5 )。结论 :重度妊娠高血压综合征并发腹水病情极为严重 ,应及时终止妊娠 ,分娩后腹水可消退 ;早期、系统、定期的产前检查可及时发现、预防重度妊高征及并发症的发生。

Objective:To analyse the feature of severe pregnancy induced hypertesion(PIH)complicated by ascites,and to discuss the diagnosis and treatment.Methods:Patients with severe PIH between January 1996 and December 2002 in our hospital were divided into group A(148 cases) which had severe PIH with ascites and group B(156 cases) which had severe PIH without ascites ,and compared their feature.Results:The gestatinal age for delivery,laboratory measure of hepatic function (Total protein、Albumin 、Albumin /Globulin,LDH,Plasma creatinine),Proteinurina in a 24-hour collecction,the proportion of intrauterine fetal death,neonatal mortality, and maternal complications in group A were different significantly compared with group B(P<0.05).Conclusions:His highrisk for fetal and mother with severe PIH complicated by ascites,and it is also an indication for termination of pregnancy as soon as possible.After delivery,the ascites gradually disappeared about a week.Early and regular systematic prenatal care is useful in diagnosis and prevention of severe PIH and it’s complications.