氟哌啶醇与氯丙嗪静滴治疗急性激越的对照研究

The comparision study on curing agitation by haloperidol and chlorpromazine venoclysis

目的 :对比氟哌啶醇与氯丙嗪静滴治疗急性激越的安全性及其疗效。 方法 :伴有急性激越的 180例精神分裂症患者随机分配至氟哌啶醇及氯丙嗪组治疗 ,以简明精神量表中的激越因子分及是否能自理生活作为衡量激越状态的标准。 结果 :氟哌啶醇组安全性高于氯丙嗪组 ,而总有效率两者无明显差异 ,两者副反应发生率相仿。 结论

Objective: Comparing the security and the curative effect of curing acute agitation by haloperidol and chlorpromazine venoclysis. Methods: 180 schizophrene examples accompanied with acute agitation were allocated to haloperidol and chlorpromazine venoclysis group at random. Whether he can take care of himself or not would be taken as a standard of measuring agitation condition by agitating factors of Brief Psychiatric Rating Scale (BPRS). Results: The security of the group of haloperidol was higher than the group of Chlorpromazine, but there was no obvious difference in the general effective rate. And both of the side reaction incidences were similar. Conclusions: The security of haloperidol is higher than that of Chlorpromazine.