摘要
目的 研究新生儿窒息后肺动脉压力的变化特点及临床意义 ,提供简便无创的检测方法。方法 应用彩色脉冲多谱勒超声于生后 2 4h内、3、7及 12~ 14d分别检测了 30例窒息新生儿及 2 5例正常新生儿左 /右心室射血前期、左 /右心室射血时间及其比值的变化 ,并依此推算肺动脉压力。结果 窒息与正常新生儿肺动脉压力在 2 4h内分别为肺动脉舒张压 (5 5 1± 17 3)mmHg对 (15 0± 3 0 )mmHg ,肺动脉阻力 (14 2± 3 9)mmHg/(L·min·m2 )对 (5 3± 1 3)mmHg/(L·min·m2 ) ,肺循环阻力 /体循环阻力比值 (0 84± 0 4 7)对 (0 2 7± 0 2 0 ) ,差异极显著 ,P <0 0 1。至生后 1周末 ,两组婴儿上述各指标间均无明显差异。结论 肺动脉高压是新生儿窒息的重要病理生理变化 ,在生后 1周内应重视对窒息新生儿肺动脉压力的检测。多谱勒超声心动图简便、无创 。
Objective To observe the variation of pulmonary arterial pressure in asphyxiated neonates by using echocardiography.Methods The left/right ventricle pre-ejection phase (LPEP?RPEP),left/right ventricle ejection time(LVET?RVET) and LPEP/LVET?RPEP/RVET were determined in 30 asphyxiated neonates at day 1,day 3,day 7 and day 12~14 after birth,the same indexs were measured in 25 health controls at day 1 to day 7 after birth and the pulmonary arterial pressure was calculated by using these indexs.That is pulmonary arterial diastolic pressure (PADP),pulmonary arterial resistance (PAR),pulmonary arterial/systemic resistance ratio(PAR/RS).Results The PADP were (55.1±17.3),(25.1±9.2),(15.7±3.4),(15.1±2.4)mmHg respectively at a continuous assessment from day 1 to day 12~14 after birth in asphyxiated neonates,whereas (15.0±2.4)mmHg in controls.PAR and PAR/RS of asphyxiated neonates were (14.2±2.9),(8.6±1.1),(5.6±1.1),(5.3±1.7)mmHg/(L·min·m 2) and (0.84±0.47),(0.50±0.31),(0.27±0.20),(0.27±0.20),while (5.3±1.3)mmHg/(L·min·m 2) and (0.27±0.20) in controls.Conclusion It was concluded that pulmonary hypertension was an important pathophysiologic process in neonatal asphyxia.Pulsed echocardiography can be used for the assessment of pulmonary arterial pressure in neonates.
出处
《小儿急救医学》
2004年第5期287-289,共3页
Pediatric Emergency Medicine
关键词
婴儿
新生
窒息
肺动脉压力
超声心动图
Infant, newborn
Asphyxia
Pulmonary arterial pressure
Echocardiography