脑脂肪栓塞的MRI诊断价值

The clinical value of MRI in the diagnosis of cerebral fat embolism

目的 :研究MRI对脑脂肪栓塞的影像学诊断及其临床价值。方法 :回顾性分析了 2 5例经临床诊断为脂肪栓塞综合征 (FES)的脑部MRI资料。MRI检查采用 0 3T、0 5T低场强设备 ,行常规SET1WI、FSET2 WI和FIFLAIR ,16例病人在发病后 1～ 3月内行MRI复查 ,CT检查 2 2例。结果 :脑脂肪栓塞 (CFE)的MRI表现为散在多发、对称分布的点、片状等或长T1长T2 信号灶 ,边缘多较模糊 ,主要位于基底节区、脑干深部、深部白质及分水岭区白质。MRI复查示随脑内病灶的吸收 ,病人症状得到不同程度的改善 ,因此 ,MRI对判断预后及指导治疗具有重要意义。结论 :MRI可为CFE的诊断提供直接的证据 。

Objective: To investigate the MRI diagnosis and clinical value of c erebral fat embolism (CFE).Methods:MR I data of 25 patients with clinically pro ved to be FES were analyzed retrospectively. MRI were performed on 0 3T and 0 5T low-field scanners. Spin-echo sequence T 1-weighted imaging, fast spin-e c ho T 2-weighted imaging and fluid attenuated inversion recovery were acquired in all cases. Follow-up examinations were done in 16 of the group. 22 patients had CT studies.Results:The MRI finding s of CFE demonstrated symmetrical multi- foci lesions with iso-or long T 1 and long T 2, mainly located in basal gangl ion, brain stem,fnterior or watershed white matter.Symptoms were improved with resolution of lesions on follow-up.MRI is of great importance for prognosis an d treatment.Conclusion:MRI provid es direct proofs in the diagnosis of CFE therefore can be the routine approach.