鼻咽癌单纯放疗与化疗加放疗的疗效比较(附1511例临床分析)

Comparative Analysis of the Efficacy of Treatment of Combined Radiotherapy and Chemotherapy with Simple Radiotherapy in Patients having Nasopharyngeal Carcinoma (NPC) (A report of 1511 cases)

本文报告从1974年至1984年收治经病理证实的鼻咽癌1511例。单纯放疗的共829例,化疗加放疗的共682例。两组对比分析发现鼻咽癌的原发灶复发率,淋巴结与远处转移,两组的生存率有明显的关系。

The conbined treatment of radio-therapy with chemotherapy was conducted from 1974 through 1984 on 1511 NPC patients. A total of 682 patients were alloted to the combined group and 829 to the control group (Radiotherapy only). All patients were followed up for more than 7 years. The 3 year, 5-year, 10-year and 15-year's survival rate of the combined group was 82%, 66.9%, 48.7% and 11.6%, respectively, and that of the control group was 49.10%, 29.0%, 17.2% and 1.8% respectively (p<0.05). The local recurrenece rate of these two groups were 9.8% (67/682)and 26.8%(222/829)respectively. The distant metastasis rate of the combined group (26.8％—183/682)was much lower than that of the control group(52.8%—438/829), p<0.05.