丽江产红景天的化学成分研究

CHEMICAL STUDY ON RHODIOLA FROM LIJIANG

从丽江产红景天粗提物中分离得到了 14个化合物 ,经波谱数据分别鉴定为二十六烷醇 (1 hexa cosanol,1) ,β 谷甾醇 (β sitosterol,2 ) ,胡萝卜苷 (daucosterol,3) ,酪醇 (tyrosol,4 ) ,红景天苷 (salidroside ,5 ) ,没食子酸 (gallicacid ,6 ) ,山奈酚 (kaempferol,7) ,草质素 7 O (3″ β D 葡萄糖基 ) α L 鼠李糖苷 (rhodiosin ,8) ,德钦红景天苷 (rhodionin ,9) ,对羟基苯甲酸 (4 hydroxybenzoicacid ,10 ) ,geranyl 1 O α L arabinopyranosyl(1→ 6 ) β D glucopyranoside(11) ,2 ,7 anhydro β D heptul opyranoses(thealtroisomer,12 ) ,乙酸二十六烷醇酯 (cerotylac etate ,13) ,1,2 ,3,4 ,6 五没食子酰基 β D 吡喃葡萄糖 (1,2 ,3,4 ,6 pentagalloyl β D glucopyranose ,14 )。根据分离所得的单体 ,用HPLC对商业化粗提物色谱中的 8个峰进行了指认 ,并测定了云南千山生物工程有限公司利用不同工艺流程所得四批粗提物中红景天苷的含量。

Fourteen compounds were isolated from the crude extracts of Rhodiola from Lijiang.They were identified as 1-hexacosanol(1),β-sitosterol(2),daucosterol(3),tyrosol(4),salidroside(5),gallic acid(6),kaempferol(7),rhodiosin(8),rhodionin(9),4-hydroxybenoic acid(10),geranyl 1-O-α-L-arabinopyranosyl(1→6)-β-D-glucopyranoside(11),2,7-anhydro-β-D-heptulopyranoses(12),cerotyl acetate(13),1,2,3,4,6-penta-galloyl-β-D-glucopyranose(14)by MS, 1H NMR and 13 C NMR data.With the isolated salidroside,the content of commercial crude extracts of Rhodiola from Lijiang were determined.At the same time,eight compounds were confirmed in the HPLC chromatrograph of commercial crude extracts of Rhodiola from Lijiang.