重度苯中毒骨髓检查及其临床诊断价值的研究

Study on the bone marrow examination and its value for clinical diagnosis in severe benzene poisoning cases

目的 探讨骨髓涂片及活检对重度苯中毒的诊断和鉴别诊断意义。方法 对 46例重度苯中毒进行骨髓穿刺 ,取骨髓液及活体组织进行研究。结果 46例有 2 3例骨髓像符合再生障碍性贫血 (AA)的典型表现 ,11例为可疑AA。苯中毒患者的骨髓涂片中粒红比值、巨核细胞数量随着骨髓增生程度降低而降低。

Objective To assess the value of bone marrow smear and biopsy examinations on diagnosis and differentiate diagnosis of severe benzene poisoning. Methods Bone marrow smear and biopsy in 46 benzene poisoning cases were analyzed. Results Of the 46 cases, 23 were aplastic anemia, 11 were suspected aplastic anemia. Bone marrow hypoplasia coincided with the reduction of the ratios of granulocytes to erythrocytes as well as the megakaryocytes count. Conclusion Bone marrow biopsy and smear examination are valuable for the diagnosis and estimation of benzene poisoning.