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不同血清群型钩端螺旋体DNA的限制性内切酶谱分析 被引量:1

Restriction Endonuclease Analysis of Leptospiral DNA from Different Serogroup and Serovar
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摘要 用7种限制性内切酶分析了不同血清群型钩端螺旋体DNA间的遗传差异。结果表明:CfoI和Eco RI的消化酶谱分辨效果较好,各血清型钩体间多存在明显差异,但同血清型的不同株之间酶谱基本相同。 The DNAs of different sero-groups and serovars of leptospires wereanalyzed with seven kinds of restrictionendonuclease (Bam HI, Bgl Ⅱ, Cfo Ⅰ,Eco RI, Hind Ⅲ, Kpn Ⅰ and Pst Ⅰ).The results showed that there are signifi-cant differences among the leptospiralDNAs of different serovars, especially inthe high molecular-weight region, but thepatterns of different strains belonging tothe same serovar are similar.In addition,Cfo Ⅰ and Eco RI are more effective fordifferentiating leptospires.
出处 《华西医科大学学报》 CAS CSCD 1993年第3期258-261,共4页 Journal of West China University of Medical Sciences
基金 国家自然科学基金~~
关键词 钩端螺旋体 限制性内切酶 DNA Leptospira DNA Restriction endonuclease analysis
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参考文献1

  • 1魏曦,钩端螺旋体病学,1982年

同被引文献12

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