摘要
目的:观察苦荞麦复方对Ⅱ型糖尿病大鼠胰岛素抵抗(IR)及血瘀症相关指标(TG、TCh)的影响。方法:给大鼠静脉注射一定量的链脲佐菌素(STZ)并配合高热量饮食的方法,造成Ⅱ型(非胰岛素依赖型)糖尿病模型。结果:苦荞麦复方在减轻症状、防止肥胖、降低血糖及提高胰岛素敏感性,改善血瘀症相关指标等方面效果均优于或接近优降糖,且对糖尿病慢性并发症发生发展有防治作用,未发现有任何毒、副作用。
Objective: To observe the effect of Fagopyrum tatarium complex prescription on insulin resistance and indexes of blood stasis such as TG, TCh in type Ⅱ diabetes rats. Method: To obtain type Ⅱdiabetes rat model, rats were injected 25 mg/kg STZ and fed on high energy feed. Results: Fagopyrum tataricum complex prescription (FTCP) was close or super to glyburide on reieving symptoms, preventing obesity, decreasing blood glucose level, improving insulin-sensitivity and blood stasis symtoms. FTCP could also prevent chronic complication of diabetes. No toxicity or side effect of FTCP was found.
出处
《中药材》
CAS
CSCD
北大核心
2001年第6期424-426,共3页
Journal of Chinese Medicinal Materials
