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细胞DNA损伤应激反应中丝裂原活化蛋白激酶的信号通路 被引量:2

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摘要 丝裂原活化蛋白激酶 (MAPKs)途径是细胞遗传毒性应激反应中主要的信号转导途径之一 ,它主要包括ERK ,JNK/SAPK ,p38等通路。各条通路都通过特异的MAPK信号级联放大反应使细胞形成应对DNA损伤的应激反应 ,从而保证细胞的正常生长和DNA复制的保真度。
出处 《国外医学(生理病理科学与临床分册)》 2004年第5期438-441,共4页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
基金 国家重点基础研究发展规划项目 ( 973 ) ( 2 0 0 2CB912 5 0 1) 国家自然科学基金 ( 3 0 3 0 0 2 77)。
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