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热休克蛋白90在心血管系统中的作用 被引量:5

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摘要 热休克蛋白 90作为一种应激性蛋白和伴侣蛋白 ,参与体内多种信号蛋白的成熟、折叠、活化、稳定及定位。热休克蛋白 90在心血管疾病中的作用涉及eNOS和MAPK家族。热休克蛋白 90对eNOS的作用主要通过与eNOS结合影响NO的合成 ,并调节NO与O2 之间的平衡 ;通过调节NO的产生而影响血小板的聚集 ;此外 ,热休克蛋白 90还对NO的下游蛋白sGC有直接作用。热休克蛋白
出处 《国外医学(生理病理科学与临床分册)》 2004年第5期473-475,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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