子宫平滑肌肉瘤34例临床分析

Clinical analysis of 34 cases of uterine leiomyosarcoma

目的 通过分析子宫平滑肌肉瘤患者的临床特点,探讨其发生的可能的高危因素。方法 回顾性分析34例术前拟诊为子宫平滑肌瘤或盆腔肿物,术中、术后组织病理为子宫平滑肌肉瘤的病例的临床特点。结果 围绝经期妇女,特别是绝经较晚、多产的妇女,子宫增大超过9 cm×8 cm,子宫肌层有血流信号的不规则回声>5 cm,有较大可能发生子宫平滑肌肉瘤。结论 妇女体内的高雌激素水平很可能为子宫平滑肌肉瘤发生的高危因素。

Objective To find the possible high-risk factors causing uterine leiomyosarcoma through analyzing the characteristics of the patients. Methods Retrospective analyses were made in 34 cases, who had been diagnosed as uterine leiomyoma or other pelvic tumors before operation and the final diagnoses were uterine leiomyosarcoma according to the pathological findings during or after operation. Results Perimenopausal women, especially those who had a late menopause or were multipara, and the women whose uteri were enlarged to the size of over 9 cm x 8 cm and ultrasonic examination suggested irregular echo > 5 cm with blood flow signs in myometrium, were likely to develop uterine leiomyosarcoma. Conclusion High concentration of estrogen is likely to be the high-risk factor causing uterine leiomyosarcoma.