期刊文献+

2001年~2003年重庆市18家医院头孢菌素类药物利用分析 被引量:10

Analysis of Cephalosporins Consumption in 18 Hospitals of Chongqing During 2001~2003 Period
下载PDF
导出
摘要 目的为医院头孢菌素类药物应用管理提供依据。方法对2001年~2003年重庆市18家医院头孢菌素类药物的品种、用药金额、用药频度(DDDs)等进行统计分析。结果3年中,头孢菌素类药物的用药金额年平均增长率为23.34%;第三代头孢菌素类药物约占50%,用量最大;2003年与2001年比较,第三代头孢菌素类药物DDDs上升540.49%,日用药金额则下降75.22%;第四代头孢菌素类药物年用药金额<2%,用量<03%。结论第三代头孢菌素类药物用量剧增,为减少细菌耐药性的发生,应尽快采取措施防止滥用该类药物。 OBJECTIVE:To provide a basis for management of use of cephalosporins in hospital METHODS:The cephalosporins used in 18 hospitals of Chongqing in 2001~2003 were statistically analysed in respect to the kind,consumption sum and DDDs etc RESULTS:During the 3-year period,the sum of cephalosporins consumption increased with an annual rate of 23 34%,of which the third generation cephalosporins were the maximum consumption in kind accounting for 50% of total cephalosporins used Compared to those in 2001,DDDs of the third generation cephalosporins increased 540 49%,but DDDc decreased 75 22% As for fourth generation cephalosporins,the annual sum and consumption were under 2% and 0 3% respectively CONCLUSION:The consumption of the third generation cephalosporins has increased sharply In order to reduce and delay the bacteria resistance,it is very important to make measures as soon as possible to control the cephalosporins abuse strictly
出处 《中国药房》 CAS CSCD 2004年第11期678-680,共3页 China Pharmacy
关键词 头孢菌素 耐药性 用药分析 cephalosporin antibiotic-resistance analysis of drug use
  • 相关文献

参考文献10

  • 1[1]Ariffin H, Navaratnam P, Kee TK, et al. Antibiotic re_ sistance patterns in nosocomial gram- negative bacterial infections in units with heavy antibiotic usage[J]. J Trop Pediatr, 2004, 50( 1): 26.
  • 2[2]Anderson AD, Nelson JM, Rossiter S, et al. Public he_ alth consequences of use of antimicrobial agents in food animals in the United States[J]. Microb Drug Resist, 2003, 9( 4): 373.
  • 3[3]Guillemot D. Antibiotic use in humans and bacterial re_ sistance[J]. Current Opinion in Microbiology, 1999, 2: 494.
  • 4[4]Austin DJ, Kristinsson KG, Anderson RM.The relatio_ nship between the volume of antimicrobial consumption in human communities and the frequency of resistance [J]. Proc Natl Acad Sci USA, 1999, 96( 3): 1 152.
  • 5罗羽,夏培元,王仙园,殷春红.临床分离黄杆菌属细菌产β内酰胺酶及耐药性分析[J].中华烧伤杂志,2004,20(1):14-16. 被引量:8
  • 6[6]Pena C, Pujol M, Ardanuy C, et al. Epidemiology and su_ ccessful control of a large outbreak due to Klebsiella pneumoniae producing extended- spectrum beta- lacta_ mases[J]. Antimicrob Agents Chemother, 1998, 42( 1): 53.
  • 7[7]Rahal JJ, Urban C, Horn D, et al. Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella[J]. JAMA, 1998, 280( 14): 1 233.
  • 8夏培元,肖光夏.细菌对抗生素的耐药性—— 一个必须面对的严重问题[J].中华烧伤杂志,2001,17(2):7-10. 被引量:24
  • 9[9]Livermore D. Can better prescribing turn the tide of re_ sistance?[J]. Nat Rev Microbiol, 2004, 2( 1): 73.
  • 10景莉,曾仁杰,赵晓丹.230例围手术期患者预防性应用抗菌药调查与分析[J].中国药房,2004,15(4):228-230. 被引量:39

二级参考文献37

共引文献66

同被引文献37

引证文献10

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部