摘要
目的探讨肾移植患者他克莫司血药浓度与效应关系,定性分析影响他克莫司血药浓度的各种因素。方法收集我院2000年～2001年80例肾移植患者他克莫司血药浓度达稳态后谷浓度数据,并作回顾性分析。结果与结论他克莫司有效血药浓度与疗程有关,肾移植术后2wk内,他克莫司血药浓度宜为12～15ng/ml,2wk以后应为8～15ng/ml。
OBJECTIVE:To investigate the relationship between Tacrolimus blood concentration and effectiveness after renal transplantation and to find factors affecting Tacrolimus blood concentration METHODS:Steady-state trough concentrations of Tacrolimus were collected from 80 renal transplantation patients RESULTS:The effective blood concentration of Tacrolimus was associated with course of treatment CONCLUSIONS:The therapeutic concentration of Tacrolimus was between 12ng/ml and 15ng/ml during the first 2 weeks after renal transplantation,then should be 8ng/ml～15ng/ml
出处
《中国药房》
CAS
CSCD
2004年第11期682-683,共2页
China Pharmacy
关键词
他克莫司
肾移植
血药浓度
Tacrolimus
renal transplantation
blood concentration
