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脉冲电流电磁场对淋巴细胞微核率影响的实验研究 被引量:2

The Experimental study of PCEMFs on micronucleus rate of human lymphocytes
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摘要 通过不同模式的脉冲电流电磁场PCEMFs对离体的人体外周血淋巴细胞进行电磁辐射,初步得出PCEMFs对淋巴细胞微核率MNR的影响的规律:细胞MNR和破坏的程度与PCEMFs的磁感应强度Bm以及其变化梯度dB dt呈正相关关系,并提出使细胞SCE发生变异的临界参考指标,其中Bm为0 15T,dB dt为1 8×104T s;而破坏的临界参考指标分别为2 64T和3 3×104T s,为强电流脉冲放电环境的电磁防护研究提供了实验依据。细胞SCE和破坏的程度和PCEMFs中电场和磁场的空间相对位置有关,电场和磁场相互垂直的PCEMFs对细胞的影响程度比其它结构形式的PCEMFs显著。 The human peripheral lymphocytes were placed in different models of radiated PCEMFs environments, and the elementary experimental results illustrate that SCE (sister chromatid exchange) and breaking of the human lymphocytes are mainly related to the magnetic induction amplitude B_m and its rising gradient dB/dt of PCEMFs. The critical reference values of MNR are put forward, where the critical reference values of aberrance refer to 0.15T (B_m) and 1.8×10~4T/s (dB/dt), and the values of damage approach to 2.64T(B_m) and 3.3×10~4T/s(dB/dt) respectively. These data can provide a criterion to study electromagnetic protection in high pulsed current discharging environment. MNR and damage of the human lymphocytes are obviously dependent upon the space structure of pulsed electric and magnetic fields, and the PCEMFs where the electric field is orthogonal to the magnetic fields have more notable influence than others.
出处 《电工电能新技术》 CSCD 2004年第4期73-77,共5页 Advanced Technology of Electrical Engineering and Energy
关键词 脉冲电流电磁场 微核率 临界参考指标 PCEMFs (pulsed current electromagnetic fields) MNR (micronucleus rate) critical reference values
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