原发性甲状腺机能减退症56例临床分析

Clinical Study on 56 cases of Primary Hypothyroidism

目的 分析原发性甲减的临床特征及误诊原因。方法 回顾性分析 5 6例原发性甲减病例资料。结果 ①4 0岁以上原发性甲减的发生率为 6 0 .71% ,与其他年龄组比较有显著性差异 (P <0 .0 5 ) ;②原发性甲减的病因依次为特发性粘液性水肿 (占 6 0 .71% ) ,桥本氏甲状腺炎 (占 19.6 4 % )、医源性甲减 (占 19.6 4 % )。与其他病因相比有显著性差异 (P <0 .0 5 ) ;③原发性甲减的误诊率为 4 4 .6 4 %。结论 原发性甲减好发于中老年患者 ,女性多于男性 ,以特发性粘液性水肿居多 ,较易误诊。对原因不明的浮肿及诊断为某系统疾病经充分治疗 ,仍有浮肿及体重增加时 。

Objective To analyze clinical features of primary hypothyroidism and causes of misdiagnosis.Methods Fifty-six cases of primaty hypothyroidism were reviewed. Results ①Occurrence of primary hypothyroidism in adults over 40 was 60.71%(P<0.05);②60.71% of the cases self-represent as unidentified edema,Hashimoto thyroiditis and iatrogenic hypothyroidism respectively accounts for 39.28% of the total(P<0.05);③44.64% of the cases were misdiagnosed.Conclusion Primary hypothyroidism is more likely to afflict the aged people and women bear higher risk; the majority of the patients have unidentified myxeodema and are likely to be misdiagnosed; hypothyroidism should be considered when unidentified edema persists and weight begins to increase after receiving comprehensive treatment.