LC意外胆囊癌的研究现状

Status quo of researches of LC and unsuspected gallbladder carcinoma

随着LC的普及 ,意外胆囊癌因其极易发生转移、预后极差而引起人们关注。文献报道LC的UGC发生率在 0 15 %～ 2 85 %之间 ,高龄、结石病史长等胆囊癌高危因素与UGC相关。切口种植转移为典型的临床病理表现 ,从一系列临床与基础相关研究发现 ,LC的术中操作和人工气腹对种植转移起着重要作用。国内外学者对UGC的处理提出了各自的观点 ,尚需更多临床资料的验证。外科医师应当警惕UGC并积极预防切口种植的发生。

More and more cholecystectomies have been laparoscopically performed in the world. Unsuspected gallbladder carcinoma (or unexpected/incidental gallbladder carcinoma, UGC) is defined as carcinoma of the gallbladder firstly diagnosed at the histological examination of the resected gallbladder. Contrary to the common gallbladder carcinoma, the metastasis of UGC is earlier and more severe and the outcome is worse. UGC is found in 0.15%-2.85% of the cases. High age and history of stones are the risk factors for gallbladder carcinoma and they are related to UGC. A series of clinical and basic researches showed port site metastasis and that surgical handling and pneumoperitoneum play an important role in the metastasis. For control of UGC, there are many different suggestions from researchers at home and abroad. Nevertheless, we will wait for the best and most effective method. Therefore, surgeons must pay close attention to UGC and prevent port-site tumor seeding.