载体红细胞及其靶向化疗的研究进展

Carrier erythrocytes and its application in targeting chemotherapy

红细胞作为一种新型的药物载体 ,因其理想的生理学和形态学特性及良好的生物相容性和生物降解性特点而日益受到重视。载体红细胞可应用于缓释给药、酶替代疗法及靶向给药等 ,经过特殊处理的载体红细胞具有更优秀的网状内皮系统靶向性 。

Erythrocytes, the most abundant cells in human body with excellent physiologic and morphologic characteristics, have been exploited extensively for their potential applications as drug delivering microspheres for several potential applications, including intravenous slow release of therapeutic agents, enzyme replacement therapy and drug targeting therapy. A series of methods has been tested successfully for the improvement of targeting to reticuloendothelial system.