慢性宫颈炎合并人乳头瘤病毒16/18型感染临床分析

A clinical study of chronic cervicitis and human papilloma virus 16/18 infection

目的 研究慢性宫颈炎合并高危人乳头瘤病毒 (HPV) 16 /18型的感染情况。方法 宫颈细胞学正常并经病理证实的慢性宫颈炎患者 15 1例 ,根据宫颈拭子HPV 16 /18检测结果分为HPV 16 /18(+)组和HPV 16 /18(- )组 ,分析患者年龄、临床表现、阴道镜检查结果 ,并对全部病例予宫颈激光治疗。结果 HPV 16 /18阳性 2 1例 ,阳性率为 13 91% ,两组患者年龄、临床表现差异无显著意义 ,HPV(+)组异常阴道镜图像多 ,经激光治疗半年后 ,宫颈光滑 17例 ,占 80 95 % ,HPV 16 /18转阴 16例 ,转阴率为 76 19%。结论 对合并高危HPV感染的慢性宫颈炎患者予以治疗 ,去除病灶 ,对预防宫颈癌有积极意义。

Objective To study the infection state of high risk human papilloma virus 16/18 in chronic cervicitis.Methods According to the result of determination of HPV 16/18,151 cases of chronic cervicitis were divided into two groups,group-A:HPV 16/18 positive and group-B:HPV 16/18 negative.The age and clinical manifestation and colpocopic signs were analyzed,and all patients were treated by laser.Results 21 cases were HPV 16/18(+) with a positive rate of 13.91%.Compared with group B,the age and clinical manifestation in group A were not prominen,but majority of colpocope observation showed atypical transformation.After treatment of laser,16 cases(76.19%) showed a negative turn of HPV after half of one year.Conclusion The active treatment for HPV-positive case with chronic cervicitis may be a important measure to prevent cervical carcinoma.