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缺血性卒中溶栓治疗中的经颅多普勒监测 被引量：2

Transcranial Doppler Monitoring During Thrombolysis for Ischemic Stroke
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摘要 经颅多普勒 (TCD)在脑梗死溶栓治疗中应用广泛。溶栓前 ,TCD可判断动脉闭塞部位 ,帮助选择合适的溶栓病例 ;在溶栓中和溶栓后 ,监测血管再通并记录微栓子信号。此外 ,TCD尚具有促进栓子溶解的作用。 Transcranial Doppler (TCD) has been widely used during thrombolytic therapy for cerebral infarction. TCD can determine the site of the occluded arteries and help to select appropriate cases for thrombolysis; it can monitor vascular recanalization and detect microembolic signal during and after the thrombolysis. In addition, it also has the effect on promoting thrombolysis.
作者 刘祖佑 徐恩 陆雪芬
机构地区 广州医学院神经科学研究所
出处 《国外医学（脑血管疾病分册）》 2004年第8期612-615,共4页 Foreign Medical Sciences Cerebrovascular Diseases
关键词 溶栓治疗 经颅多普勒 TCD 监测 缺血性卒中 栓子 血管再通 记录 transcranial Doppler ■ cerebral infarction ■ thrombolysis
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献18

  • 1Alexandrov AV, Demchuk AM, Felberg RA, et al. High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial doppler monitoring. Stroke, 2000, 31:610 -614.
  • 2Christou I, Alexandrov AV, Burgin WS, et al. Timing of recanalization after tissue plasminogen activator therapy determined by transcranial Doppler correlates with clinieal recovery from ischemic stroke. Stroke, 2000, 31:1812 - 1816.
  • 3Felberg RA, Okon NJ, EI-Mitwalli A, et al. Early Dramatic Recovery During Intravenous Tissue Plasminogen Activator Infusion: Clinical Pattern and Outcome in Acute Middle Cerebral Artery Stroke.Stroke, 2002, 33:1301 - 1307.
  • 4Demchuk AM, Burgin WS, Christou I, et al. Thrombolysis in brain ischemia (TIBI) transcranial Doppler flow grades predict clinical severity, early recovery, and mortality in patients treated with intravenous tissue plasminogen activator. Stroke, 2001, 32:
  • 5Del zoppo GJ, Higashida RT, Furlan AJ, et al. PROACT: a phase Ⅱ randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. PROACT Investigators.Prolyse in Acute Cerebral Thromboembolism. Stroke, 1998
  • 6The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med, 1995, 333:1581 - 1587
  • 7Demchuk AM, Christou I, Wein TH, et al. Accuracy and criteria for localizing arterial occlusion with transcranial Doppler. J Neuroimaging, 2000, 10:1 - 12.
  • 8Burgin WS, Malkoff M, Felberg RA, et al. Transcranial doppler ultrasound criteria for recanalization after thrombolysis for middle cerebral artery stroke. Stroke, 2000, 31:1128 - 1132.
  • 9Alexandrov AV, Demchuk AM, Feberg RA, et al. Intracranial clot dissolution is associated with embolic signals on transcranial Doppler. J Neuroimaging, 2000, 10:27 -32.
  • 10Demchuk AM, Felburg RA, Alexandrov AV. Cllirical recovery from acute ischemic stroke after early reperfusion of the brain with intravenous thrombolysis. N Engl J Med, 1999, 340: 894- 895.

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国外医学（脑血管疾病分册）
2004年 第8期

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