高血压病患者血浆神经降压素和神经肽Y水平的临床意义

Significance of plasma neurotensin and neuropeptide levels in patients with Hypertension

目的 :探讨高血压病患者血浆神经降压素 (neurotensin,NT)和神经肽 Y (neuropeptide Y,NPY)变化的临床意义。方法 :用放射免疫法测定了我院高血压病人 6 0例的 NT、 NPY。结果 :对照组 NT、 NPY分别为 74 .3± 2 6 .5、 145.1± 2 4 .2 pg/ ml,明显低于高血压 期病人 (135.8± 17.4、 170 .2± 2 7.4 pg/ ml) ,P<0 .0 1,0 .0 5。结论 :NT、

Objective:To study significance of plasma nurotensin(NT) and neuropeptide(NPY) levels in essential hypertension(EH).Methods:By means of radioimmunoassay studied the changes of plasma neurotensin and neuropeptide Y in 60 cases.Results:Plasma NT and NPY of EHⅢ(135 8±17 4,170 2±27 4 all in pg/ml) were significantly higher than that control.Conclusion:Measured content of NT and NPY in essential hypertension may be helpful to diagnose hypertension and evaluate prognosis. Author′s address Sanming First Hospital,Sanming,Fujian province,365000