取代二苯醚的新合成反应及历程研究

Investigation on the New Synthetic Reactions and Mechanisms of Substituted Diphenyl Ethers

在碱金属亚硝酸盐和碳酸盐存在下,被强吸电子基团取代的硝基苯在非质子极性溶剂中能发生自身缩合反应,生成结构对称的双取代二苯醚,收率较高。此类反应的主要历程属于S_NA_r,但同时也存在着S_(RN)A_r(SET)历程作为次要途径。

In the present of alkali nitrite and carbonate, some nitrobenzenes substituted by strongly electron withdrawing groups undergo a self condensation in an aprotic polar solvent to give symmetrical disubstituted diphenyl ethers in good yields. A possible mechanism is discussed, the nucleophilio aromatic substitution S_NAr and S_(RN)Ar (SET) may occur simultaneously.