吸烟对血清总胆红素浓度的影响及其致冠心病作用

Effect of cigarette smoking on serum total bilirubin and its effect in inducing coronary heart disease

目的:探讨吸烟对血清总胆红素(TB)浓度的影响及其在致冠心病中的作用。方法:将符合条件的154例行冠脉造影术的病人分为吸烟组(81例)与不吸烟组(73例),测定血清总胆红素浓度,分析组间血清TB水平差异。按冠脉造影的结果将此154例病人重新分组:冠脉造影正常组(63例),冠脉造影中度狭窄组(21例),冠脉造影高度狭窄组(70例),分析组间血清TB水平差异。结果:吸烟组血清TB浓度显著低于不吸烟组(P<0.05)。冠脉高度狭窄组及冠脉中度狭窄组的TB水平显著低于冠脉造影正常组(P<0.05-<0.01)。结论:吸烟可显著降低血清总胆红素水平,从而增加冠心病发病危险。

Objective: To explore the effect of cigarette smoking on serum total bilirubin (TB) and its effect in inducing coronary heart disease. Methods: A total of 154 patients who had undergone coronary angiography entered the study. They were divided into smoking group (81 cases) and no smoking group (73 cases). Their serum TB concentration were measured and compared. According their results of coronary angiography they were divided into three groups: (1) severe stenosis;(2)middle stenosis; (3)normal. Their serum TB concentration was compared. Results: The serum TB concentration of smoking group was significantly lower than that of no smoking group (P<0. 05). The serum TB concentrations of severe stenosis and middle stenosis groups were significantly lower than that of normal group (P< 0. 05-<0. 01) . Conclusion:Cigarette smoking may significantly reduce the serum total bilirubin concentration and raise the risk of CHD.