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中枢兴奋剂莫达非尼 被引量:3

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摘要 莫达非尼(modafini)是一种新型的中枢兴奋型α,受体激动剂,主要用于治疗自发性嗜睡症和发作性睡眠症。本文对本品的药理作用、药动学特征、药物相互作用与不良反应进行了简单介绍,并对本品的多项临床研究进行了总结综述。
作者 张衡
出处 《世界临床药物》 CAS 2004年第10期631-633,共3页 World Clinical Drug
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参考文献8

  • 1Chariot J,Appia F,Vaille C,et al.Effect of modafinil on pancreatic excrine secretion in rats: a comparison with adrafinil and related drugs[].Fundamental and Clinical Pharmacology.1987
  • 2Robertson P Jr,Hellriegel T,Arora S,et al.Effect of modafinil at steadystate on the single-dose pharmacokinetic profile of wafarin in healthy volunteers[].Journal of Clinical Pharmacology.2002
  • 3Hellriegel ET,Arora S,Nelson M,et al.Steady-state pharmacokinetics and tolerability of modafinil given alone or in combination with methylphenidate in healthy volunteers[].Journal of Clinical Pharmacology.2001
  • 4Hellriegel ET,Arora S,Nelson M,et al.Steady-state pharmacokinetics and tolerability of modafinil given alone or in combination with dextroamphetamine in healthy volunteers[].Journal of Clinical Pharmacology.2001
  • 5Saletu B,Frey R,Krupka M,et al.Differential effects of a new central adrenergic agonist modafinil and d-amphetamine on sleep and early morning behavior in young healthy volunteers[].International Journal of Clinical Pharmacology Research.1989
  • 6Bastuji H,Jouvet M.Successful treatment of idiopathic hypersomnia and narcolepsy with moadfinil[].Progress in Neurology and Psychiatry.1988
  • 7Rugio TA,Copley T.Effects of modafinil in children with attention-deficency/hyperactivity disorder: An open-label study[].J Am Acd Child Adolesc Psychiatry.2001
  • 8Taylor FB,Russo J.Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults[].Journal of Child and Adolescent Psychopharmacology.2000

同被引文献15

  • 1王睿,方翼,周筱青,柴栋,王中孝,王林,金义光,彭涛.单次口服莫达芬尼片在中国健康志愿者的药代动力学[J].中国临床药理学杂志,2004,20(4):278-282. 被引量:8
  • 2杨进波,赵明.种族差异对药代动力学影响的研究进展[J].中国临床药理学杂志,2005,21(3):225-228. 被引量:16
  • 3Burnat P, Robles F, Do B. High-performance liquid chromatographic determination of modafinil and its two metabolites in human plasma using solid-phase extraction [J]. J Chromatogr B Biomed Sci Appl, 1998, 706(2): 295-304.
  • 4Schwertner HA, Kong BS. Determination of modafinil in plasma and urine by reversed phase high-performance liquidchromatography [J]. J Pharm Biomed Anal, 2005, 37 (3) : 475-479.
  • 5Mckenzie RE, Elliott LL. Effects of secobarbital and damphetamine on performance during a simulated air mission [ J ]. Aeospace Med , 1965,36(4) :774
  • 6Caldwell JA, Caldwell JL. Fatigue in military aviation : an overview of US military-approved pharmacological countermeasures [ J ]. Aviat Space Environ Med ,2005,76 (7) :C39
  • 7Westoctt KJ. Modafinil, sleep deprivation, and cognitive function in military and medical settings[J]. Mil Med ,2005,170(4) :333
  • 8FERRARO L, TANGANELLI S, THOMAS W, et al. The vigilance promoting drug modafinil decreasesGABA release in the medial preptic area in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor [J ]. Neurosci Lett, 1996, 220(1):5- 11.
  • 9NANCYWONG Y, PETER S, WATSON B, et al. Single-dose pharmacokinetics of modafinil and methylphenidate given alone or in combination in healthy male volunteers [ J ]. Clin Pharmacol, 1998, 38 : 276 - 282.
  • 10NANCY WONG Y, PETER S, WATSON B, et al. Single-dose pharmacokinetic study of modafinil tablet: influence of age and gender in normal subjects [ J ]. Clin Pharmacol, 1999, 39: 281 - 288.

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