多巴胺和肾上腺素合用在心脏停搏复苏中的作用

Clinical effect of dopamine combination with epinephrine on the treatment of cardiac arrest

目的 探讨多巴胺和肾上腺素联合应用在心脏停搏复苏中的作用。方法 2 0例心跳骤停患者给予多巴胺和肾上腺素联合用药 ,2 6例心跳骤停患者单用肾上腺素作为对照组。比较两组患者的心脏电活动和自主循环恢复情况。结果 合用组恢复心电活动 16例 (80 %) ,高于单肾上腺素组 46.15 %(12 /2 6) ,差异有显著性 (P <0 .0 5 ) ;合用组恢复自主循环 15例 (75 %) ,也高于单用肾上腺素组 42 .3 %(11/2 6) ,差异也有显著性 (P<0 .0 5 )。结论 较大剂量多巴胺与肾上腺素联合用药在心脏停搏患者中的疗效优于单纯使用肾上腺素。

Objective To determine clinical effect of dopamine combination with epinephrine in the treatment of cardiac arrest. Methods 46 patients were divided into two groups: 20 patients with cardiac arrest received intravenous epinephrine and dopamine in the experimental group, and 26 cases only received epinephrine in the control group. Electrical activity,spontaneous circulation were compared. Results 16(16/20, 80%) cases in the experimental group and 12(12/26, 46.15%) cases in the control group recovered electrical activity of cardiac. 15(15/20, 75%) cases in the experimental group recovered spontaneous circulation compared to 11(11/26, 42.3%) cases in the control group. The results were different (P<0.05).Conclusion The results suggested that clinical effects of dopamine combination with epinephrine in the treatment of cardiac arrest may be better than those of only epinephrine.