摘要
目的 探讨胃癌术中淋巴结的标记方法。方法 2 2 4例胃癌患者随机分为 3个组 :美蓝 抗胃癌单克隆抗体 (MAb3H 11)注射组 (观察组 ) 76例 ;美蓝组 73例 ;对照组 75例。结果 观察组 76例清扫淋巴结 2 2 0 1个 ,平均每例清扫 2 9.0个 ,平均每例清扫转移淋巴结 7.8个 ( 5 93 / 76) ;美蓝组 73例清扫淋巴结 1619个 ,平均每例清扫 2 2 .2个 ,平均每例清扫转移淋巴结 6.0个( 4 41/ 73 ) ;对照组 75例清扫淋巴结 13 77个 ,平均每例清扫 18.4个 ,平均每例清扫转移淋巴结 4.9个 ( 3 68/ 75 ) ;平均每例清扫的淋巴结数及转移淋巴结数 ,观察组均明显多于美蓝组和对照组 (P <0 .0 1)。结论 应用美蓝 抗胃癌单克隆抗体 (MAb 3H 11)术中胃壁注射 。
Objective To study the method of intraoperative lymph nodes marking in patients with gastric cancer.Methods 224 patients with gastric cancer were randomly divided into 3 groups to receive either methylene blue and monoclonal antibody 3H11(MAb 3H11)marking(n=76),or methylene blue marking(n=73),or no marking(n=75).Results The average resected lymph nodes of each patient was 29.0 in group with MAb3H11 marking,22.2 in group with the methylene blue marking and 18.4 in the control group(P<0.01).The average resected lymph nodes metastases were 7.8 in group with MAb3H11 marking,6.0 in group with the methylene blue marking and 4.9 in the control group(P<0.01).Conclusion The method of intraoperative injection of MAb 3H11 in the gastric wall can effectively mark the gastric field lymph nodes for patients with gastric cancer.
出处
《实用癌症杂志》
2004年第4期413-414,417,共3页
The Practical Journal of Cancer
