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终末期肾功能衰竭维持性血液透析患者血清瘦素与甲状旁腺素的关系

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摘要 【目的】探讨终末期肾功能衰竭维持性血液透析患者血清瘦素与甲状旁腺素的关系。【方法】检测29例终末期肾功能衰竭维持性血液透析患者体脂含量、血清白蛋白、球蛋白、胆固醇、甘油三酯、肌酐、尿素氮、甲状旁腺素和瘦素,多重直线逐层分析法筛选出对血清瘦素有影响的指标。【结果】终末期肾功能衰竭维持性血液透析患者女性体脂及瘦素显著高于男性患者,血清瘦素与体脂呈正相关(γ=100.30),与甲状旁腺素水平呈负相关(γ=-0.0149),女性患者甲状旁腺素与瘦素/体脂负相关(γ=-0.454,P=0.045),男性患者甲状旁腺素与瘦素/体脂无显著性相关(γ=-0.454,P=0.832)。【结论】终末期肾功能衰竭维持性血液透析女性患者血清瘦素与甲状旁腺素水平呈负相关,甲状旁腺素可能参与调节瘦素的分泌。
出处 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2004年第B07期329-331,共3页 Journal of Sun Yat-Sen University:Medical Sciences
基金 广东医学科学技术研究基金(A200022)
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