The Odontogenic Jaw Cysts: Analysis of the Clinical Parameters of 669 Cases

目的 :分析、比较三型牙源性颌骨囊肿的临床特点。方法 :收集 2 0年间牙源性角化囊肿 (odontogenickera tocyst ,OKC)、根端囊肿 (radicularcyst,RC)及含牙囊肿 (dentigerouscyst,DC)的临床资料 ,对其性别构成、年龄分布、发病部位及临床表现等进行比较研究。结果 :1)三型颌骨囊肿的男女之比分别为 :OKC 1.6∶1,RC 1.4∶1,DC 4 .1∶1(χ2 检验 ,P <0 .0 0 5 )。 2 )除DC未见于 70岁以上年龄段外 ,几乎各年龄段均见三型颌骨囊肿的发生 ,三型囊肿组间及组内的年龄分布均有显著性差异 (χ2 检验 ,P <0 .0 0 5 )。OKC及RC2 0～ 2 9岁年龄段患病人数最多 ,分别占各年龄段患病人数的 2 7%及 2 0 % ;DC10～ 19岁年龄段患病人数最多 ,占各年龄段患病人数的 2 9%。 3)颌骨的任一部位均见三型颌骨囊肿的发生 ,但发生频率不同 ,三型颌骨囊肿组间及组内发病部位的分布有显著性差异 (χ2 检验 ,P <0 .0 0 5 )。 4 )OKC有 137例合并感染 ,感染率 39% ;RC4 8例合并感染 ,感染率 2 4 % ;DC18例合并感染 ,感染率 16 % ,三型间有显著性差异 (χ2 检验 ,P <0 .0 0 5 )。结论 :1)男性较女性更易发生牙源性颌骨囊肿。 2 )不同的年龄段 ,对OKC、RC及DC的易感性不同。OKC及RC发生的高峰期均为 2 0～ 2 9岁年龄段 ;DC发生的高峰?

Objective: Radicular cyst (RC), dentigerous cyst (DC), and odontogenic keratocyst (OKC) are most common odontogenic jaw cysts (OJC). Methods: In order to compare their clinical features, a retrospective study of 669 cases of OJC was designed including the gender composition, age distribution, localization, and clinical presentation of OKC, RC, and DC, and the results were statistically analyzed with chi-square test. Results: The male: female ratio of OKC was 1.6∶1, RC 1.4∶1, and DC 4.1∶1 (P<0.005). The incidence of OJC was seen in almost all age groups except that DC was not seen in 70+ years group. The age distribution had a significant difference among the three kinds of OJC or in each cyst group (P<0.005). The incidence rate of OKC or RC in the third decade was the highest among that of all age groups (OKC, 27%; RC, 20%); the incidence rate of DC in the second decade was the highest (29%).The three kinds of OJC were seen in all areas of the jaw with a different frequency, and the involved locations had significant differences among the three kinds of OJC or in each cyst group (P<0.005). 137 cases of OKC, 48cases of RC , and 18 cases of DC were secondarily infected (infection rate: OKC, 39%; RC, 24%; DC, 16%)( P<0.005). Conclusions: These results suggest that (1)male predilection appears in OJC; (2)the peak incidence of OKC or RC is the third decade, and that of DC is the second decade; (3)a different location of the jaw has a different susceptibility for OKC, RC, or DC-the predilection localization of OKC is mandibular molar-premolar region, and that of RC or DC is maxillary anterior region; (4)the symptom of infection is helpful for the differential diagnosis among OKC, RC and DC.