1Pour PM, Konishi Y, Kloeppel G, et al. Staging for carcinoma of the pancreas: Japanese stage classification compared to UICC stage classification Atlas of exocrine pancreatic tumors. New York: Springer-verlag, 1994.247-264.
2Shimiza M, Saitoh Y, Ohyanagi H, et al. Immunohistochemical staining of pancreatic cancer with CA19-9 Kmol, unabsorbed CEA and absorbed CEA a compa-rison with normal pancreas and chronic pancreatitis. Arch Pathol Lab Med, 1990,114:195-199.
4Scheper RJ, Broxterman HJ, Scheffer GL, et al. Overexpression of a 110 kD vesicular protein in non-p-glycoprotein mediated multidrug resistance. Cancer Res, 1993,53:1745-1749.
5Scheffer GL, Wijinga PLJ, Flens MJ, et al. The drug resistance-related protein LRP is the human major vault protein. Nat Med, 1995,1:578-582.
6Chugani DC, Rome LH, Kedorsha NL. Evidence that vault ribonucleoprotein particles localizes to the nuclear pore complex. J Cell Sci, 1993,106:23-29.
7Attern J, Volm M. Multiple pathway drugs resistance (review). Int J Oncol, 1993, 2:557-561.
8Miguel A, Izquierdo MA, George L, et al. Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors. Am J Pathol,1996, 148:877-886.
5Cascinu S, Berardi R, Labianca R, et al. Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer:a randomised, multicentre, phase Ⅱ trial. Lancet Oncol,2008,9:39-44.
6Nieth C, Priebsch A, Stege A, et al. Modulation of the classical muhidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Lett,2003,545 : 144-150.
7Lage H. ABC-transporters: implications on drug resistance from microorganisms to human cancers. Int J Antimicrob Agents,2003, 22 : 188-199.
8Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Bioehim Biophys Acta, 1976,455 : 152-162.
9Cordon Cardo C, O' Brien JP, Boccia J, et al. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J Histochem Cytochem, 1990,38:1277- 1287.
10Lu Z,Kleeff J, Shrikhande S, et al. Expression of the muhidrugresistance 1 ( MDR1 ) gene and prognosis in human pancreatic cancer. Pancreas,2000,21:240-247.