摘要
目的 通过对与人类生活密切相关的多种野生、驯化和圈养动物携带SARS样病毒状况的研究 ,比较与野生动物密切接触人群和健康人群SARS病毒感染率 ,研究探索SARS病毒的来源。 方法 于 2 0 0 3年 5月起在广东等7个省自治区调查并采集动物咽漱液、鼻拭子和肛拭子样本 ,进行细胞培养、IFA、荧光RT -PCR检测 ;分析不同动物携带SARS样病毒状况。 结果 2 0 0只动物样本检出 10只动物携带SARS样病毒 ,其中主要是果子狸 (9只、阳性率为7 96% )。 1740名人员血清的SARSIgG抗体总阳性率为 5 0 6% ,其中野生动物销售人员最高 (4 5 45 % ) 结论 研究结果支持SARS病毒来源于动物 (果子狸 )的假设 ,并推测SARS病毒能从动物传播给人类。
Objective To study the source of SARS virus by investigating the condition of whether the wild, tamed and domestic anminals carry SARS virus and to compare the SARS virus infection rate in population closedly contacted with animals. Methods From May 2003 on, throat swabs, nasal swabs and fecal swabs were collected from animals in 7 provinces of Guangdong, Guangxi, Fujian and so on for cell culture, IFA and RT-PCR detection. The SARS virus carrying condition of different animals were analyzed. Results 10 animals from 200 animals were detected positive, and among them, 9 were civet cat (the positive rate was 7.96%).Among 1740 people who closedly contacted with animals, the positive rate of SARS IgG was 5.06%;people who sale wild animals had the highest positive rate of 45.45%. Conclusion The results could support the hypothesis that SARS virus were originated from animals(especially civet cat) and could infer that SARS virus might spread from animal to human.
出处
《中国热带医学》
CAS
2004年第6期916-918,共3页
China Tropical Medicine
基金
国家 973项目 (2 0 0 3CB51 4 1 0 1 )
