摘要
目的 探讨胃液中癌胚抗原(CEA)、糖链多肽抗原19-9(CA19-9)在胃癌预后判断和复发筛查中的价值。方法应用免疫放射法检测了62例胃癌患者(术后复发组32例,未复发组30例)手术前后胃液中CEA、CA19-9变化,并进行随访观察。结果复发组CEA为(65.81±43.62)ng/ml,CA19-9为(172.53±159.38)U/ml。两组比较,有非常显著差异(P<0.01)。CEA、CA19-9联检可将敏感性提高至81.25％,并可在胃癌术后亚临床期检出复发。结论 胃液CEA、CA19-9联检对胃癌疗效观察、预后判断和复发筛查具有重要意义。
Objective To explore diagnostic value of combining detection of CEA and CA19-9 in gastric juice for prognosis and relapse in operated gastric cancer. Methods 62 cases suffering from advanced gastric cancer has been studied using immunoradiometric assay method and followed-up. Results In 32 cases of relapsed cancer the values of CEA and CA19-9 were (65. 81±43. 62)ng/ml and (172. 53±159. 38)U/ml respectively. They were significant higher (P <0.01) in relapsed than un-relapsed gastric cancer group. The sensitivity can be increased by 81.25% using the combining detection and detect the relapse in post-operation of gastric cancer in the sub-clinical stage. Conclusion The combining detection of CEA and CA19-9 in gastric juice has an important point to curative effect,prognosis and filtration for gastric cancer.
出处
《山东医药》
CAS
北大核心
2004年第30期17-18,共2页
Shandong Medical Journal
基金
济南铁路局科研基金资助课题(NO.01Y45-3)
