胰激肽原酶与神经妥乐平治疗糖尿病周围神经病变疗效比较

Comparision of Therapeutic Effiect of Diabetes Accompanied by Peripheal Neuropathy Treated with Pancreatic Kininogenase and Neurotropin

目的 :观察胰激肽原酶与神经妥乐平对糖尿病周围神经病变的治疗作用。方法 :186例给予胰激肽原酶 12 0u ,po ,tid ,连服 30d为一疗程 ;36 5例给予神经妥乐平 7.2u加入 0 .9%氯化钠注射液 2 5 0ml静滴 ,qd ,连续 15d为一疗程。结果 :胰激肽原酶组总有效率 5 5 .9%。神经妥乐平组总有效率 6 3.9%。两组比较 ,疗效无统计学差异 (P >0 .0 5 )。结论

Objective: To compare the therapeutic effect of pancreatic kininogenase and neurotropin in treatment of diabetes complicated with peripheal neuropathy .Method: 186 cases were given pancreatic kininogenase 120 u, po,tid,therapy duration was 30 days; 365cases were given neurotropin 7.2 u plus 0.9% sodium chloride injection 100 ml ivd, qd,the theapy duration was 15 days.Result: The total efficacy rate in pancreatic kininogenase group was 55.9% ; while that neurotropin group was 63.9% . There was no significant difference in two groups( P > 0.05 ).Conclusion: The pancreatic kininogenase and neurotropin have obvious therapeutic effects on diabetes complicated with the peripheal neuropathy.