奥硝唑的合成

Preparation of Ornidazole

用2-甲基-5-硝基咪唑、环氧氯丙烷和少量浓硫酸在甲酸中于0～5℃反应10h得到奥硝唑,收率51%。

Ornidazole was prepared from 2-methyl-5-nitroimidazole and epichlorohydrin in formic acid with con-centrated sulfuric acid as catalyst at 0～5℃ for 10h in a yield of 51%.