磁共振弥散加权成像检测肝内小病灶的临床应用

Clinical application of diffusion-weighted MR imaging in detecting small liver foci

目的 评估弥散加权成像 (DWI)检测肝内小病灶能力。方法 对 10 3例有肝脏局灶性病变 (直径均≤ 2cm )的患者行DWI、常规MRI平扫及动态增强 ,分别计数DWI与常规MRI检出≤ 2cm肿瘤结节的个数。计算在DWI与T2WI上病灶与肝组织之间的对比噪声比 (CNR)并予以比较。结果 DWI共显示肝内小病变 42 5个 ,T2WI显示 2 17个 ,增强MRI显示 2 11个 ,T1WI显示 15 5个 ,DWI显示的小病灶的数目明显多于T2WI、增强与T1WI (P <0 .0 5 )。在DWI及T2WI序列 ,小病灶与肝组织之间的CNR分别为 10 .45± 3 .16和 7.5 8± 2 .60 (P <0 .0 5 )。结论 与常规MRI比较 。

Objective To evaluate capability of diffusion-weighted imaging (DWI) technique in detecting small liver foci. Methods DWI, routine non-enhanced MRI and dynamic contrast enhanced MRI were used in 103 patients with hepatic local lesions smaller than 2.0 cm in diameter. The number of the lesions detected by DWI, T1WI, T2WI and dynamic contrast enhancement were counted respectively. Contrast noise ratio (CNR) between lesion and liver tissue for DWI and T2WI were measured. Results The detected lesions were 425 in DWI, 217 in T2WI, 211 in contrast enhancement and 155 in T1WI. The number of the detected lesions in DWI was significantly larger than that in other sequences ( P <0.05). With regard to CNR between lesion and liver tissue, there was significant difference ( P <0.05) between DWI (10.45±3.16) and T2WI (7.58±2.60). Conclusion Compared with routine MRI, DWI is a sensitive method for detecting small liver foci.