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肾脏及肾肿瘤CT灌注初步研究 被引量:6

Preliminary application of CT perfusion in kidney and renal tumor
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摘要 目的 探讨肾脏及肾肿瘤的CT灌注成像方法及价值。方法 对 11例受检者肾脏进行同层动态扫描。扫描参数包括 :层厚 3mm ,在对比剂注射后第 7s开始扫描 ,间隔扫描时间为 3s ,共扫描 12层 ,对比剂按 1ml/kg计算给药 ,经肘前静脉单相注射 ,注射流量为 3ml/s。取得正常肾脏 (n =13 )及肾肿瘤 (n =9)血流量 (BF)图。结果 正常肾皮质BF为(15 7.3± 2 0 .5 )ml/(min·10 0ml) ,恶性肿瘤BF为 (85 .4± 43 .8)ml/(min·10 0ml)。 Objective To study the value of CT perfusion in kidney and renal tumor. Methods The single-section CT dynamic scan was performed on 9 patients with renal tumors (8 malignant and 1 benign) and 2 healthy subjects with following scan parameters: 7 s delay, 3 s scan interval, total 12 images. Contrast medium was given at the flow rate of 3 ml/s from forearm superficial vein at 1 ml/ kg. Time-density curves and blood flow (BF) graphics of 9 renal tumors and 13 normal kidneys were then obtained. Results The mean BF in renal cortex was (157.3±20.5) ml/(min·100 ml), different from that of malignant renal tumors [85.4±43.8 ml/(min·100 ml)]. Conclusion CT perfusion can be used to quantify the blood flow of kidney and renal tumor.
出处 《中国医学影像技术》 CSCD 2004年第10期1523-1525,共3页 Chinese Journal of Medical Imaging Technology
基金 安徽省卫生厅科研基金资助项目 (2 0 0 2B0 77)
关键词 体层摄影术 X线计算机 灌注成像 肾脏 肾肿瘤 Tomography, X-ray computed Perfusion imaging Kidney Renal tumor
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参考文献10

  • 1Miles KA. Measurement of tissue perfusion by computered tomography[J]. Br J Radiol, 1991, 64(761):409-412.
  • 2Jinzaki M, Tanimoto A, Mukai M. Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis[J]. J Comput Assist Tomogr, 2000, 24(6):835-842.
  • 3Gervais DA, McGovern FJ, Arellano RS, et al. Renal cell carcinoma: clinical experience and technical success with radio-frequency ablation of 42 tumors[J]. Radiology, 2003, 226(2):417-424.
  • 4Tsushima Y,Aoki J,Endo K, et al. Underestimation of renal cortical perfusion calculated from dynamic CT data [J].Radiology, 2002, 224(2): 613-614.
  • 5Paul JF, Ugolini P, Sapoval M, et al. Unilateral renal artery stenosis: perfusion pattern with electron-beam dynamic CT-preliminary experience[J]. Radiology, 2001, 221(1):261-265.
  • 6范光明,郭启勇.肝脏CT灌注成像的研究进展[J].中国医学影像技术,2004,20(2):298-301. 被引量:21
  • 7李智勇,伍建林.脑CT灌注成像的基本原理及在脑肿瘤研究中进展[J].中国医学影像技术,2003,19(3):373-375. 被引量:6
  • 8Anderson H, Yap JT, Wells P,et al. Measurement of renal tumour and normal tissue perfusion using positron emission tomography in a phase Ⅱ clinical trial of razoxane[J]. Br J Cancer, 2003, 89(2):262-267.
  • 9赵心明,周纯武,吴宁,罗德红,黄遥,王建卫,孙伟,梁颖.胰腺多层螺旋CT灌注研究[J].中华放射学杂志,2003,37(9):845-849. 被引量:90
  • 10余永强,郑斐群,柏亚,张诚,李旋,吴津民,孟晓梅.脑胶质瘤灌注成像与病理对照研究[J].中国医学计算机成像杂志,2001,7(3):157-159. 被引量:18

二级参考文献54

  • 1[1]Fayad PB, Brass LM. Single photon emission computed tomography in cerebrovascular disease[J]. Stroke,1991,22(7):950-954.
  • 2[2]Wirestam R, Ryding E, Lindgren A, et al. Regional cerebral blood flow distributions in normal volunteers: dynamic susceptibility contrast MRI compared with 99mTC-HMPAO SPECT[J]. J Comput Assist Tomogr, 2000,24(4):526-530.
  • 3[3]Gobbel CT, Cann CE, Fike JR. Comparison of xenon-enhanced CT with ultrafast CT for measurement of regional cerebral blood flow[J]. AJNR,1993,14(3):543-550.
  • 4[4]Roberts HC, Roberts TPL, Smith WS, et al. Multi-section dynamic CT perfusion for acute cerebral ischemia: the "toggling-table" technique[J]. AJNR, 2001, 22(6):1077-1080.
  • 5[5]Meier P, Zierler KL. On the theory of the indicator-dilution method for measurement of blood flow and volume[J]. J Appl Physiol,1954,6:731-744.
  • 6[6]Miles KA, Hayball MP, Dixon AK. Color perfusion imaging: a new application of computed tomography[J]. Lancet,1991, 337(8742):643-645.
  • 7[7]Hamberg LM, Hunter GJ, Halpem EF, et al. Quantitative, high resolution measurement of cerebral vascular physiology with slip-ring CT[J]. AJNR,1996,17(4):639-650.
  • 8[8]Axel L. Cerebral blood flow determination by rapid sequence computed tomography: theoretical analysis. Radiology, 1980, 137(3):679-686.
  • 9[9]Peters AM, Gunasekera RD, Henderson BL, et al. Non-invasive measurements of blood flow and extraction fraction[J]. Nucl Med Commun, 1987, 8(10):823-837.
  • 10[10]Klotz E, Konig M. Perfusion measurements of the brain: using dynamic CT for the quantitative assessment of cerebral ischemia in acute stroke[J]. Eur J Radiol,1999, 30(3):170-184.

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