北京市部分职业人员血脂水平及血脂异常流行情况

The serum lipid levels and the prevalence of dyslipidemia in some parts of Beijing professionals

目的:分析2003年北京部分职业人员血脂水平及高脂血症的患病率,并与国内1984～1986年有关血脂研究资料及日本、美国血脂调查结果比较。方法:以16963名体检者为研究对象,对其进行问卷调查、体检及血脂指标检测,血脂包括总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)。结果:由于TC、HDL-C、LDL-C及TG数据呈偏态分布,按百分位数法得出各年龄组的血脂结果,统计血脂异常的不同性别和年龄组的流行率。与20年前相关研究结果比较,男女TC高0.09mmol/L及0.11mmol/L,TG增高明显,男女分别为0.47mmol/L和0.3mmol/L,LDL-C差异无显著性,HDL-C下降0.07mmol/L(男)和0.05mmol/L(女)。高脂血症患病率比20年前明显增高,TC高于合适水平者有27.4%,高TC检出率为14.2%。本统计TC水平比日本低0.55mmol/L,比美国低0.53mmol/L(男)和0.56mmol/L(女),差异均具有显著性(P<0.001)。结论:与20年前资料相比,各型血脂异常检出率明显上升。TG升高幅度较大,而TC水平较稳定。目前我国冠心病血脂危险水平仍低于日本和美国。

Objective To determine the serum lipid levels and the prevalence of lipid abnormalities in some parts of Beijing career staff in 2003,and compare these data with those during the last 2 decades in China,Japan and America. Methods 16 963 people were enrolled in this study, whose healthy behavior and medical history were taken by questionnaires. Serum lipid levels including total cholesterol(TC),low and high-density lipoprotein cholesterol(LDL-C and HDL-C) and triglyceride(TG) were measured. Results The data of TC, HDL-C, LDL-C and TG presented a skew distribution. Compared with the previous data from 1984 to 1986, the TG levels increased significantly (0.47 mmol/L in males and 0.3 mmol/L in females) and the HDL-C levels decreased significantly (0.07 mmol/L in males and 0.05 mmol/L in females); however, the TC and the LDL-C levels remained unchanged. The variations of TC,LDL-C and HDL-C in different age groups were less significant than that of TG. There existed significant difference in the prevalence of dyslipidemia in different gender and age groups. Compared the corresponding data in Japan and America,the TC levels were lower in China. Conclusions The prevalence of dyslipidemia increases significantly during the last 2 decades in China. The lipid risk for coronary disease in Chinese is still lower than that in Japanese and American.