肺结核病人中HIV感染监测结果初步分析

Primary analysis of HIV infection in patients with pulmonary tuberculosis

目的 了解肺结核病人中艾滋病病毒 (HIV)感染情况。方法 对监测点的活动性肺结核病人用酶联免疫吸附试验 (ELISA)进行HIV初筛 ,初筛阳性者做免疫印迹 (WB)确认试验。结果 15 6 9例肺结核病人中 ,HIV感染者 15例 ,占 0 96 %。HIV感染病人年龄在 16～ 6 2岁 ,男性组HIV感染率 1 2 % ,女性组感染率为 0 4 1% ,差异无显著的统计学意义 (χ2 =2 2 3,P >0 0 5 )。痰结核菌涂片阳性和阴性的肺结核病人HIV感染率为 0 4 8%和1 9% ,差异有显著的统计学意义 (χ2 =7 4 3,P <0 0 5 )。结论 肺结核病人中HIV感染率较高 ,应加强对肺结核病人的HIV监测。

Objective To understand the state of HIV infection in patients of pulmonary tuberculosis.Method The primary screening of HIV infection was done by ELISA,and final screening of HIV infection was taken by WB.The subjects to be investigated were cases of pulmonary tuberculosis.Result The rate of HIV infection was 0.96%(15 cases) in all the 1 569 patients of pulmonary tuberculosis.The rates of HIV infection was 1.2% and 0.41% in male and female aged 16-62 years,The two groups had no statistic difference(χ2=2.23,P>0.05).The rates of HIV infection in sputum smear(+) and sputum smear(-) were 0.48% and 1.9% respectively,and the two groups had statistic difference(χ2=7.43,p<0.05).Conclusion The rate of HIV infection in patients of pulmonary tuberculosis is higher,and the pulmonary tuberculosis is a focus of investigation for HIV infection.