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基质金属蛋白酶-2与颈动脉粥样硬化的研究进展 被引量：1

Progress of study on matrix metalloproteinase-2 with carotid atherosclerosis
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摘要 基质金属蛋白酶-2(matrix metalloproteinase-2,MMP-2)又称白明胶酶A,它表达广泛,能够降解明胶、多种胶原和基底膜成分,对于平滑肌细胞的增殖和迁移起着重要作用.这些作用推动了颈动脉粥样硬化(carotid atherosclerosis,CAS)的形成和进展[1].本文将MMP-2及其与颈动脉粥样硬化关系的研究进展作如下综述.
作者 刘力峰 郭春杰 曲怀谦
机构地区 山东省聊城市人民医院神经内科
出处 《中国脑血管病杂志》 CAS 2004年第11期521-525,共5页 Chinese Journal of Cerebrovascular Diseases
关键词 颈动脉粥样硬化 基质金属蛋白酶-2 MMP-2 研究进展 明胶酶A 基底膜 胶原 重要作用
分类号 R543.4 [医药卫生—心血管疾病]
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参考文献34

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同被引文献19

  • 1[2]Chow AK,Cena J,Schulz R.Acute actions and novel targets of matrix metalloprotoinases in the heart and vascalature.Br J Phar-macology,2007,152:189-205.
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  • 7[8]Boyd PJ,Doyle J,Gee E,et al.Mitogen-activated protein kinase signaling regulates endothelial cell assembly into networks and the expression of MT1-MMP and MMP-2.Am J Physiol Cell Physiol,2005,288:C659-C668,
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中国脑血管病杂志
2004年 第11期

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