井冈霉素发酵染菌的研究和制服方法

Exploring and Methods of Control Bacterial-Infection of Validamycin-Ferntation

染菌是井冈霉素发酵生产工艺中最为棘手的问题,同时也是直接影响产品质量、提取收率和成本的关键因素.通过对生产工艺中种子、培养基和设备及其附件等各个工段的染菌原因分析,综合多年来积累的生产实践经验,总结出了制服井冈霉素生产工艺中染菌的一套行之有效的办法.

Bacterial-infection is the most serious problem in the technology of Validamycin production and a key factor to infect directly the quality, output and production cost of Validamycin. By terms of bacterial-infection industrial analyzing of vaccine, culture medium, equipments appendixes and all process, and synthesizing production experience accumulated for many years, the author has summarized a series of effective methods of control bacterial-infection of Validamycin production.