卵磷脂络合碘治疗中心性浆液性脉络膜视网膜病变

Effects of Jolethin on central serous chorioretinopathy

目的 观察卵磷脂络合碘治疗中心性浆液性脉络膜视网膜病变的疗效。方法 4 2例经临床及荧光素血管造影 (FFA)确诊为中心性浆液性脉络膜视网膜病变患者随机分为两组 ,治疗组 2 3例 ,用卵磷脂络合碘 ,1 5mg/次 ,3次 /d ,共 2个月 ;对照组 19例 ,用肌苷片 ,2 0 0mg/次 ,3次 /d ,共 2个月。观察治疗前后视力、眼底变化、视野及FFA改变。结果 1例淘汰。有效率治疗组 90 9% ,对照组 36 8% (P <0 0 1)。结论 卵磷脂络合碘对中心性浆液性脉络膜视网膜病变有明显疗效。

Objective To investigate the effects of jolethin on central serous chorioretinopathy(CSC).Methods 42 patients with CSC diagnosed by clinic and fundus fluorescein angiography(FFA) were randomly divided into two groups.23 patients(23 eyes) as treatment group received jolethin three times a day for 2 months and 19 patients(19 eyes) as control group received inosine three times a day for 2 months.The changes of visual acuity,ophthalmoscopic sign,visual field and FFA before and after treatment were observed.Results 1 patients(1 eye) loss of follow up.The effective rate was 90.9% in the treatment group and 36.8% in the control group(P<0.01).Conclusion Jolethin has remarkable effects in the treatment of CSC.