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抑制血管紧张素Ⅱ药物的肾保护研究 被引量：5

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摘要 肾素血管紧张素系统 (RAS)是重要的内分泌系统 ,血管紧张素Ⅱ是该系统最主要的效应因子 ,它影响着肾脏疾病进展的各个环节 ,而越来越多的研究也表明应用血管紧张素转化酶抑制剂 (ACEI)或血管紧张素受体 1拮抗剂 (AT1RA)阻断血管紧张素Ⅱ的效应可以延缓肾脏疾病的发展 ,有效改善预后。本文就阻断血管紧张素Ⅱ药物的肾保护作用及应用研究作一综述。
作者 周楠 沈颖
机构地区 首都医科大学附属北京儿童医院
出处 《国外医学（泌尿系统分册）》 2004年第6期807-810,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 肾疾病 血管紧张素Ⅱ 血管紧张素转化酶抑制药
分类号 R692 [医药卫生—泌尿科学]
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参考文献21

  • 1Border WA, Noble NA. Interactions of transforming growth factor - [ beta]and angiotensin Ⅱ in renal fibrosis. Hypertension, 1998,31:181 - 188.
  • 2Ruiz - Ortega M,Lorenzo O, Suzuki Y, et al. Proinflammatory actions of angiotensin Ⅱ. Curr Opin Nephrol Hypertens,2001,10:321 - 329.
  • 3Ruiz - Ortega M, Lorenzo O, Ruperez M, et al. Angiotensin Ⅱ activates nuclear trsnscription factor [kappa]B through AT1 and AT2 in vascular smooth muscle cells: molecular mechanisms. Circ Res. 2000; 86:1266 1272.
  • 4Graciano ML, Cavaglieri Rde C, Delle H, et al. Intrarenal Renin- Angiotensin system is upregulated in experimental model of progressive renal disease induced by chronic inhibition of nitric oxide synthesis. J Am Soc Nephrol,2004,15(7): 1805- 15.
  • 5Durvssula RV, Petermann AT,Hiromura K, et al. Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int,2004,65(1):30-9.
  • 6Nabokov A, Amann K, Gassmann P, et al. The renoprotective effect of angiotensin - converting enzyme inhibitors in experimental chronic renal failure is not dependent on enhanced kinin activity. Nephrol Dial Transplant,1998,13(1):173-6.
  • 7Lee AA, Dillmann WH, McCulloch AD, et al. Angiotensin Ⅱ stimulates the autocrine production of transforming growth factor - β1 in adult rat cardiac fibroblasts. J Mol Cell Cardiol, 1995,27:2347- 2357.
  • 8Kumar S, Babiker OE, Tracy AM, et al. Captopril - induced reduction of serum levels of transfonming growth factor - beta correlates with long -term renoprotection in insulin dependent diabetic patients. Am J Kidney Dis, 1999,34(5) :818 - 823.
  • 9Wuhl E, Mehls O, Schaefer F, et al. Antihypertensive and antiproteinuric efficacy of ramiprilin children with chronic renal failure. Kidney Int,2004,66(2) :768 - 76.
  • 10Noris M, Mister M, Pezzotta A, et al. ACE inhibition limits chronic injury of kidney transplant even with treatment started when lesions are established. Kidney Int, 2003,64(6): 2253 - 61.

同被引文献26

  • 1胡茂清,张执玉.糖尿病肾病的合理治疗[J].四川省卫生管理干部学院学报,2005,24(4):286-289. 被引量：6
  • 2孙世澜,曾红兵.老年人糖尿病肾病的治疗[J].中华老年医学杂志,2006,25(1):18-19. 被引量：25
  • 3覃志成,陈洪宇.复方积雪草对高IgA血清诱导小鼠肾足细胞表达VEGF的影响[J].中国中医药科技,2006,13(5):307-308. 被引量：13
  • 4王迎新,魏伟,雷红,方永红,陈敏珠.黄芪复方对大鼠阿霉素肾病防治作用的研究[J].中国中医药科技,2007,14(3):154-155. 被引量：9
  • 5Laverman GD, Remuaai G, Ruggenenti P. ACE inhibition versus angiotensin receptor blockade:which is better for renal and cardiovascular protection[ J]. J Am Soc Nephrol ,2004 ,15 :64-70.
  • 6[2]Makino H,Nakamura Y,Wada J.Remission and regression of diabetic nephropathy[J].Hypertens Res,2003,26(7):515-519.
  • 7[6]Gilbert RE,Cox A,Wu LL,et al.Expression of transforming groth-factor-β1 and type Ⅳcollagen in the tubulointerstitrum in experimental diabetes effects of ACE inhibition[J].Diabets,1998,47(3):414-422.
  • 8[7]Ulicna O,Cizova M,Kolesar P,et al.Bioenergetics of livermitochondria after administration of ramipril in experimental diabetsmellitus[J].Bratisl Lek Listy,1997,98(12):687-691.
  • 9[8]Lew is EJ,Hunsicker LG,ClarkeWR,et al.Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropatay duo to type 2 diabeters[J].NEngl JMed,2001,345(12):851-855.
  • 10[9]Laverman GD,Remuaai G,Ruggenenti P.ACE inhibition versus angiotensin receptor blockade:which is better for renal and cardiovascular protection[J].J Am Soc Nephrol,2004,15(1):64-70.

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国外医学（泌尿系统分册）
2004年 第6期

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