上皮型钙粘素与妇科肿瘤
摘要
上皮型钙粘素(E-cadherin)是一类介导同型上皮细胞黏附作用的膜表面糖蛋白,与恶性肿瘤侵袭转移密切相关。综述E-cadherin在妇科恶性肿瘤发生发展中的作用及调节机制。E-cadherin是多种妇科肿瘤侵袭转移过程中的重要因素,有望成为妇科肿瘤预后判断的标识物。
参考文献20
-
1Babb SG, Marrs JA. E-cadherin regulates cell movements and tissue formation in early zebrafish embros.Dev Dyn,2004,230(2):263-277.
-
2Byers SW, Sommers CL, Hoxter B, et al. Role of E-cadherin in the response of tumor cell aggregates to lymphatic,venous and arterial flow: measurement of cell-cell adhesion strenth. J Cell Sci, 1995, 108(5):2053-2064.
-
3Perl AK,Wilgenbus P,Dahl U,et al.A causal role for E-cadherin in the transition from adenoma to carcinoma.Nature, 1998,392:190-193.
-
4Karatzas G,Karayiannakis AJ,Syrigos KN,et al.E-cadherin expression correlates with tumor differentiation in eoloreetal cancer. Hepato Gastroenterol, 1999,46:232-235.
-
5Karatzas G ,Karayiannakis AJ,Syrigis KW,et al.Expression patterns of the E-cadherin-catenin cell-cell adhesion complex in gastric cancer.Hepato Gastroenterol, 2000,47:1-4.
-
6Fujioka T,Takebayashi Y,Kihana T,et al.Expression of E-cadherin and beta-catenin in primary and peritoneal metastatic Ovarian carcinoma.Oncol Rep,2001,8(2):249-255.
-
7Rask K, Nilsson A, Brannstrom M, et al. Wnt-signalling pathway in ovarian epithelial tumours:increased expression of beta-catenin and GSK3beta.Br J Cancer,2003,89(7): 1298-1304.
-
8Morita T,Shibata K, Kikkawa F,et al.Oxytocin inhibits the progression of human ovarian carcinoma cells in vitro and in vivo.Int J Cancer,2004,109(4):525-532.
-
9Gadducci A, Ferdeghini M, Cosio S, et al. Preoperative serum E-cadherin assay in patients with orarian carcinoma.Anticancer Res,1999,19(1B):769-772.
-
10Sundfeldt K,Ivarsson K,Rask K,et al. Higher levels of soluble E-cadherin in cyst fluid from malignant ovarian tumors than in benign cysts. Anticancer Res,2001,21(1A):65-70.
-
1马红,陈晓,马海梅,尼加提.热合木.E-cadherin和β-catenin在食管鳞状细胞癌中的表达及其意义[J].新疆医科大学学报,2008,31(5):534-536. 被引量:1
-
2仲立新.肝细胞癌上皮型钙粘素基因甲基化及其临床特征研究[J].当代医学,2014,20(14):18-19.
-
3伊铁忠,糜若然.上皮型钙粘素(E-cad)与子宫内膜癌研究的新进展[J].国外医学(妇产科学分册),2005,32(4):225-228. 被引量:2
-
4涂燕玲(综述),李晓江(审校),隋军(审校).黏附分子与鼻咽癌的侵袭和转移[J].国际肿瘤学杂志,2008,35(1):20-23.
-
5张友才,陈金霞,董培红,邓长生,陈永平.肝细胞癌上皮型钙粘素基因甲基化及其临床特征分析[J].中国肿瘤临床,2006,33(14):792-794. 被引量:2
-
6伊铁忠,糜若然,蔡雁,孙鹰,董铁军.子宫内膜癌中E-cadPTEN蛋白表达及其临床意义[J].中国肿瘤临床,2005,32(22):1271-1274. 被引量:5
-
7樊冬梅,史惠蓉,陈志敏,刘惠娜,张瑞涛.TGF-β1和E-cadherin在卵巢癌原发灶和转移灶组织中的表达与意义[J].南方医科大学学报,2010,30(6):1355-1358. 被引量:7
-
8张传海,许戈良,荚卫东,李建生,马金良,任维华,葛勇胜,刘文斌.肝细胞癌中磷酸化STAT3与上皮型钙粘素的表达及其临床意义[J].安徽医科大学学报,2011,46(2):105-108. 被引量:2
-
9耿丽,何炜.E—cadherin、N—cadherin和β-catenin在食管鳞癌组织中的表达及其临床病理学意义[J].中国实用医刊,2011,38(18):87-90.
-
10罗勇,贺大林,宁亮,朱国栋,申树林.前列腺癌细胞株LNCaP和IA8中转移相关蛋白的差异表达及意义[J].中华男科学杂志,2006,12(3):230-233. 被引量:4