安徽省流行性出血热病原学研究及其意义

Etiological study of epidemic hemorrhagic fever in Anhui province

[目的 ] 通过病原学研究为出血热防治工作提供科学依据。 [方法 ] 用病原学、血清学、RT -PCR、序列测定技术对我省出血热的宿主动物、传播途径、地理流行病学、疫区类型及新型新亚型进行分析。 [结果 ] 我省共分离出血热病毒 3 2株 ,涉及 9种宿主动物 ;气溶胶可传播实验动物型出血热 ;山林地区存在新型出血热病毒。 [结论 ] 我省是多宿主多传染源的出血热疫源地 ,以姬鼠型为主 ,流行季节以秋冬季为主 ,呈单峰型 ;山林地区存在新型出血热疫源地。

Objective] To provide scientific gist for prevention and control of epidemic hemorrhagic fever (EHF) by etiological studies. [Methods] Kinds of reservoir hosts of EHF, transmission route, geographic epidemiology, types of pestilential area of EHF and new-type EHF virus were studied by etiological methods, serological, RT-PCR and sequencial determinations. [Results] 32 strains of EHFV were isolated from 9 kinds of hosts. Aerosol could transmit EHF in experimental animals. New-type of EHF virus was detected in mountainous areas. [Conclusion] Our province is an epidemic area of EHF with multiple-hosts, among which rattus type of EHF is predominant.