老年肝病患者52例并发败血症及感染性休克的临床分析

Clinical characteristic of septicemia and septic shock in elderly patients with liver disease

目的 了解老年肝病患者合并败血症及感染性休克的临床特点。方法 选择 6 0岁以上血培养阳性的肝病患者 5 2例的病例资料进行回顾性分析总结。结果 5 2例老年肝病患者发生败血症合并感染性休克者 8例 ,占 15 4 %。发生败血症后肝、肾功能进一步恶化。 5 2株病原菌中革兰阴性菌占 71 2 % ,革兰阳性菌占 2 6 9% ,真菌占 1 9%。全组病例死亡和病情恶化自动出院者共 18例 ,占34 6 %。结论 老年肝病患者并发败血症及感染性休克使病情恶化 ,严重影响预后 ,临床应高度重视 ,进行及早正确的综合治疗和及时抢救以降低病死率。

Objective To study the clinical characteristics of septicemia and septic shock in elderly patients with liver disease. Methods Fifty-two patients over 60 years old with liver disease and positive blood culture, admitted form 1999 to 2003, were enrolled for analysis. Results Septic shock was found in 8 patients (15.4%). The course of sepsis was complicated by progressive deterioration of hepatic and renal functions. 18 patients (34.6%) died or left the hospital in a critical condition. 52 strains of pathogenic bacteria were isolated, among which 71.2% were G +germ, 26.9% G -germ and 1.9% fungi. Conclusion Septicemia and septic shock can exacerbate liver disease. Early diagnosis and treatment should be emphasized to lower the mortality.