放疗和博宁治疗骨转移癌疼痛的疗效观察

Curative Effect of Bone Metastasis Cancer Pain by Radiotherapy and Boning

目的 :对比观察骨转移癌疼痛行放疗止痛和博宁止痛的疗效。方法 :6 9例骨转移癌疼痛患者随机分为放疗组 (36例 ,局部放疗 DT 2 0 GY/5 F/1W)和博宁组 (33例 ,第 1天静滴博宁 90 mg,第 15天再静滴 6 0 mg)。结果 :放疗组与博宁组止痛有效率分别为 91.7%和 81.8% (P>0 .0 5 ) ;单发骨转移癌痛病灶放疗组与博宁组止痛有效率分别为 95 .7%和 73.3% (P<0 .0 5 ) ;多发骨转移癌痛病灶放疗组与博宁组止痛有效率分别为 84 .6 %和 88.9% (P>0 .0 5 )。结论 :放疗与博宁治疗骨转移癌疼痛都具有良好的止痛效果 ,但对单发骨转移癌痛病灶 ,应首选放疗。

Objective:To evaluate curative effect of bone metastatic cancer pain by radiotherapy and bonin.Methods:Sixty-nine patients with bone metastatic cancer pain were divided randomly into radiotherapy groups (36 cases with radiotherapy, TD 25GY/5F/1W) and boning group (33 cases with boning ,90 mg intravenous infusions d 1, 60 mg intravenous infusions d 15) .Results:The response rate of the radiotherapy group and boning group is 91.7% and 81.8% respectively (P>0.05). For single site of bone metastatic cancer pain, the response rate of radiotherapy group is 95.7%, while the Bonin group is 73.3% (P<0.05). For multiple focus of bone metastasis cancer pain, the response rate of radiotherapy group is 84.6%, while the Bonin group is 88.9% (P>0.05).Conclusion:Both radiotherapy and Bonin can relieve bone metastatic cancer pain,but,radiotherapy is more effective than Boning for single site of bone metastatic cancer pain.