期刊文献+

聋人枕叶视皮层对频率刺激反应规律的事件相关fMRI研究

Study on the Visual Cortical Response to Stimulus Frequency in Deaf with Event Related fMRI
下载PDF
导出
摘要 目的 :探讨聋人枕叶视皮层对视觉频率刺激的反应规律。材料和方法 :采用事件相关fMRI技术 ,对 8例聋人和正常人分别给予不同频率的刺激 ,通过MR采集其脑部数据 ,运用SMPM99统计软件进行处理分析。结果 :聋人与正常人的枕叶视皮层在不同频率刺激下均产生兴奋 ;随着频率的增加 ,聋人与正常人枕叶视皮层的兴奋区兴奋强度 (intensity)呈现先增加后下降并略有反弹的趋势 ,二者相似 ;聋人与正常人的最佳刺激频率分别为 4Hz和 6Hz。结论 :聋人与正常人的枕叶视皮层对频率刺激的基本反应规律是相似的 。 Purpose:To study the deaf and normal brain response various stimulus frequency rates using event related functional magnetic resonance imaging (ER fMRI), and to describe the rules of response and find the best stimulus frequency rate.Materials and Methods: Deaf subjects (n=8) and normal subjects (n=8) were stimulated by different frequency rates. The fMRI data were collected on GE 1.5 T Signa Horizon LX MRI system and analyzed by SPM99. Results: Responding to various stimulus frequency rates, significant activations were observed in occipital visual cortex in all deaf and normal subjects. For both deaf and normal subjects, the amplitude of the fMRI response increased with the stimulus frequency firstly, then declined slightly. The peaks for deaf and normal was 4Hz and 6Hz respectively. Conclusion:The brain response to visual stimulus frequency rates for deaf subjects is similar to that of normal subjects, but has some differences on the peak.
出处 《中国医学影像学杂志》 CSCD 2004年第6期445-448,共4页 Chinese Journal of Medical Imaging
关键词 正常人 视皮层 刺激反应 兴奋 处理分析 后下 聋人 频率 数据 统计软件 fMRI event related deafness visual cortex frequency 
  • 相关文献

参考文献13

  • 1Menon RS, Ogawa S, Hu X, et al. BOLD based functional MRI at 4 Tesla includes a capillary bed contribution: echo-planar imaging correlates with previous optical imaging using intrinsic signals. Magn Reson Med, 1995, 33(3): 453
  • 2Zhu XH, Kim SG, Chen W, et al. Stimultaneous oxygenation and perfusion imaging study of functional activity in primary visual cortex at different visual stimulation frequency: Quantitative correlation between BOLD and CBF changes. Magn Reson Med, 1998, 40
  • 3Yarowsky F, Kadekaro M, Sokoloff L. Frequency-dependent activation of glucose utilization in the superior cervical ganglion by electrical stimulation of cervical sympathetic trunk. Proc Natl Acad Sci, 1983, 80(13): 4179
  • 4Kwong KK, Belliveau JW, Chesler DA, et al. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulus. Proc Natl Acad Sci, 1992, 89(12): 5675
  • 5Fox PT, Raichle ME,Mintun MA, et al. Nonoxidative glucose consumption during focal physiologic neural activity. Science, 1988, 241(4864): 462
  • 6Forsyth DM, Chapanis A. Counting repeated light flashes as a function of their number, their rate of presentation, and retinal location stimulated. J Exp Psychol 1958, 56(5): 385
  • 7Cheatman PG, White CT. Temporal numerosity: I. Perceived number as a function of flash number and rate . J Exp Psychol, 1952, 44(6): 447
  • 8Thomas CG, Menon RS. Amplitude response and stimulus presentation frequency response of human primary visual cortex using BOLD EPI at 4T. Magn Reson Med, 1998,40(2): 203
  • 9Ozus B, Liu HL, Gao JH, et al. Rate dependence of human visual cortical response due to brief stimulation: An event-related fMRI study. Magn Reson Imaging, 2001, 19(1): 21
  • 10Toga A, Collins R. Metabolic response of optic centers to visual stimuli in the albino rat: anatomical and physiological considerations. J Comp Neurol, 1981, 199(4): 443

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部