愈伤灵膏的抗炎镇痛作用

Anti-inflammatory and analgesic effect of the Yushangling Ointment

目的研究愈伤灵膏的抗炎镇痛作用。方法采用血管通透性实验、小鼠耳肿胀实验、大鼠角叉菜胶性足跖肿胀实验、小鼠光热法及醋酸所致小鼠扭体反应等炎症、疼痛模型考察愈伤灵膏的抗炎镇痛作用。结果愈伤灵膏可明显抑制烫伤部位毛细血管通透性 ;对角叉菜胶致大鼠足肿胀和二甲苯致小鼠耳肿胀有明显的抑制作用 ;对光热致小鼠足部疼痛、醋酸致小鼠扭体均有明显的镇痛效果。结论愈伤灵膏具有明显的抗炎。

Objective To study anti-inflammatory and analgesic effect of the Yushangling Ointment.Methods Different pain and inflammatory models were made to investigate the anti-inflammatory and analgesic effects of the Yushangling Ointment.Results The results of the anti-inflammatory experiments showed that ear edema resulted from dimethyl benzene and paw edema induced by carragheenin were significantly inhibited by the Yushangling Ointment; permeability of micro-vessels of post-burned wound in rats and mice was greatly decreased.And the Yushangling Ointment also produced obvious analgesic effects on the pain model of body-twisting caused by acetic stimulus in mice and light-heat stimulation in mice.Conclusion The Yushangling Ointment has significant anti-inflammatory and analgesic effect.