CT引导下无水乙醇瘤内注射治疗原发性肝癌的临床研究

A Clinical Research of Anhydrous Ethanol Tumor Injection for Primary Liver Cancer under the Guide of CT

目的 探讨CT引导下经皮肝穿刺无水乙醇瘤内注射治疗原发性肝癌的疗效。方法 将 14 4例原发性肝癌患者配对设计分为两组 ,治疗组采用CT引导下经皮肝穿刺瘤内注射无水乙醇 ,对照组行综合性治疗 ,比较两组治疗效果。结果 无水乙醇瘤内注射与综合治疗后 1年及 3年患者的生存率分别为 79 2 %、 80 6 %和 4 1 7%、 38 9% (P >0 0 5 ) ,无水乙醇瘤内注射治疗后未发生严重并发症。结论 无水乙醇瘤内注射与综合治疗原发性肝癌患者的 1、 3年生存率是无差别的 ,但前者具有操作简单 ,并发症少 ,花费少 。

Objective To investigate effect of anhydrous ethanol tumor injection for primary liver cancer under the guide of CT.Methods 144 primary liver cancer cases are divided into two groups randomly, one group use anhydrous ethanol tumor injection, the other group use synthetical therapy, the difference effect was compared between the two groups.Results The survival rates of 1 year and 3 years of group1 and group2 are 79.2%, 80.6% and 41.7%, 38.9% respectively (P>0.05).There is no severe complication after anhydrous ethanol tumor injection.Conclusion There is no significant difference in survival rate of 1 and 3 years between the two groups, but the way of anhydrous ethanol tumor injection has the advantage of simpler manipulation,less chance of complication, lower medical charge, and easily accepted by patients.