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ERβ蛋白在原发性乳腺癌中的表达及其意义

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摘要 采用免疫组化PV 90 0 0法检测 46例原发性乳腺癌组织中的ERβ蛋白的表达 ,分析ERβ蛋白与乳腺癌临床病理生物学参数的关系。结果示 46例原发性乳腺癌组织中 ,ERβ的阳性表达率为5 8.7% (2 7/ 46) ,ERβ与ERα表达相关 ,在ERα(+ )组和ERα(-)组中其阳性表达率分别为 71%和3 3 .3 % ,两组差别有显著性 (P <0 .0 5 )。ERβ的表达与患者的年龄、绝经与否、肿瘤大小、淋巴结状况、组织学分级及PR均无关 (P >0 .0 5 )。ERβ表达与ERα相关 。
出处 《中国普通外科杂志》 CAS CSCD 2004年第11期864-866,共3页 China Journal of General Surgery
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参考文献9

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